Cancer - Between Glycolysis and Physical Constraint

Considerable effort has gone into the research of common cancers - lung, bowel, ovarian, cervical, and prostate cancer. In recent years, however, there has been a lack of breakthroughs in therapeutic advances. By challenging many established beliefs, Cancer explores these issues by offering new perspectives on the study of cancer and exploring the areas of mathematics, physics and chemistry in cancer research. This book is for cancer specialists, clinicians, and researchers interested in an innovative view in cancer research.

1 Introduction.- 2 Are Cancer Cells Malignant Per Se?.- 3 Cell Growth: A Balance Between Glycolysis and Physical Constraint.- 4 Extracellular Constraints Regulate Cell Differentiation.- 5 Extracellular Constraints Regulate Cell Differentiation.- 6 Hypoxia Is Responsible for Changes in Cellular Constraints During Inflammation.- 7 Fibrosis Perpetuates Hypoxia.- 8 Metastasis: The Hunt for Food.- 9 Carcinogens Target Cell Respiration and Induce Glycolysis.- 10 Epidemiology: Aging as the Main Cause of Cancer.- 11 Aging Causes Inflammation and Fibrosis Mimicking the Impact of Carcinogens.- 12 Inhibition of Metabolism Slows Aging and Decreases Cancer Incidence.- 13 A Complication of Hypoxia: The Loss of Cell Polarity Explains Cancer Cell Proliferation.- 14 The Loss of Cell Differentiation Is a Consequence of Glycolysis.- 15 Response to Treatment: A Balance Between Glycolysis and Physical Constraints.- 16 Targeting Glycolysis.- 17 Conclusion.