Chemo-Enzymatic Cascade Reactions

Explores biocatalytic-chemical cascade reactions and their applications in the synthesis of valuable chemicals.Das E-Book Chemo-Enzymatic Cascade Reactions wird angeboten von Wiley-VCH GmbH und wurde mit folgenden Begriffen kategorisiert:Biochemical Engineering, Biochemische Verfahrenstechnik, Catalysis, Chemical Engineering, Chemie, Chemische Verfahrenstechnik, Chemistry, Katalyse, Organic Chemistry, Organische Chemie

1 Introduction1.1 Advantages of Enzyme Catalysis1.1.1 Chemo-selectivity1.1.2 Regioselectivity1.1.3 Stereoselectivity1.1.4 Mild Reaction Conditions1.2 Modes of Chemo-enzymatic transformations1.2.1 "separate-pot-two-step" mode1.2.2 "one-pot-two-step" mode1.2.3 "one-pot-one-step" mode1.3 Summary and outlooks2 "Separate-Pot Two-Step" Chemo-Enzymatic Transformation2.1 Lipases2.2 Nitrilases2.3 Carbonyl reductases2.4 Ene reductases2.5. Transaminases2.6 Imine reductases2.7 Cytochromes P450s2.8 Baeyer-Villiger monooxygenases (BVMOs)2.9 Aldolases2.10 Epoxide hydrolases2.11 Other Enzymes2.12 Integration of Multi-Enzyme Cascade with Chemical Transformation2.13 Summary and outlooks3. One-Pot Sequential Chemoenzymatic Reactions3.1 Lipases and Esterases3.2 Carbonyl Reductases3.3 Ene Reductases3.4 Transaminases3.5 Epoxide hydrolases (EHs)3. 6 Other Enzymes3.6.1 Aldolases3.6.2 Halohydrin Dehalogenases3.6.3 Phenylalanine Ammonia Lyases3.6.4 D-amino Acid Dehydrogenases (DAADHs)3.6.5 Halogenases3.6.6 Imine Reductases3.6.7 Decarboxylases3.6.8 Cytochrome P450s3.6.9 Hydroxynitrile Lyases3.6.10 Nitrilases3.6.11 Laccases3.6.12 Transglutaminases3.6.13 a-Ketoglutarate-Dependent (a-KG) non-Heme Iron Oxygenases3.6.14 Galactose Oxidases3.6.15 FAD-Dependent Monooxygenases3.7 Summary and outlooks4. Chemoenzymatic Dynamic Kinetic Resolution4.1 Enzymatic Kinetic Resolution4.2 Dynamic Kinetic Resolution4.3 Racemization techniques4.4 DKR of Chiral Alcohols4.5 DKR of Chiral Amines4.6 DKR of Other Compounds5. Chemo-enzymatic Concurrent Deracemization5.1 Deracemization of Amino acids and Amines5.2 Deracemization of Hydroxy Acids and Alcohols5.3 Deracemization of Chiral Sulfoxides5.4 Summary and outlooks6. One-pot Concurrent Chemo-Enzymatic Reactions6.1 One-pot concurrent chemo-enzymatic cascades6.1.1 Lipases6.1.2 Carbonyl Reductases6.1.3 Enoate Reductases6.1.4 Transaminases6.1.5 Monoamine Oxidases6.1.6 Cytochrome P450s6.1.7 Halohydrin Dehalogenases6.1.8 Vanadium Haloperoxidases6.1.9 Laccases6.2 Integration of Chemical Reaction with Metabolism of Living Organisms6.3 One-pot Concurrent Chemo-Enzymatic Cascades via Compartmentalization6.4 Summary and outlooks7. Photo-Catalytic and Biocatalytic Cascade Transformations7.1 Photoenzymes7.2 Light-Activation of Redox Enzymes without Co-factor Regeneration7.3 Light-Activated Co-factor Regeneration for Redox Enzymes7.4 Photo-Induced Catalytic Promiscuity of Redox Enzymes7.5 Photocatalysis and Biocatalysis Cascades7.5 Summary and outlooks8. Perspectives