Inflammation

Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.

Inflammation through the Ages: A Historical PerspectivePART I: INDUCERS AND SENSORS OF INFLAMMATIONPathogen-associated Molecular PatternsDamage-associated Molecular PatternsBacterial ToxinsVenomsHypoxia as an Inducer of InflammationVaccine AdjuvantsPattern Recognition ReceptorsPART II: INFLAMMATORY CELLSMonocytes and MacrophagesNeutrophilsMast Cells: Master Drivers of Immune Responses against PathogensDendritic Cells in Inflammatory DiseaseRoles for NK Cells and ILC1 in Inflammation and Infection Group 2 and Group 3 Innate Lymphoid Cells: New Actors in Immunity and Inflammation Th9 Cells: From the Bench to the Bedside and Back AgainTh17 CellsPlateletsEpithelial CellsInflammation: The Role of Endothelial CellsPART III: INFLAMMATORY MEDIATORSIL-1 Superfamily and InflammasomeTNF Superfamily Interleukin-17 A-EIL-6 SuperfamilyType I and II Cytokine Superfamilies in Inflammatory ResponsesChemokines and ChemotaxisLipid Mediators in InflammationFree Radicals in InflammationProteasesPsychiatric Disorders and Inflammation Complement SystemHeat Shock ProteinsPART IV: INFLAMMATION AND HOST RESPONSEInflammation and Coagulation Fever: Mediators and MechanismsPainInflammation, Hormones and MetabolismMicroenvironmental Regulation of Innate Immune Cell FunctionEpigenetics of InflammationPART V: INFLAMMATION AND DISEASESAllergy and InflammationSepsisAutoimmunity and InflammationPsoriasis and Other Skin Inflammatory DiseasesRheumatoid Arthritis and Other Inflammatory Articular DiseasesMissing Heritability of Crohn's Disease and Implications for Therapeutic Targeting and Improved CareInflammation and TransplantationInflammatory Mechanisms in Chronic Obstructive Pulmonary DiseaseObesity: A Complex Disease with Immune ComponentsInflammation and Type 2 DiabetesInflammation-Mediated Neurodegeneration: Models, Mechanisms, and Therapeutic Interventions for Neurodegenerative DiseasesInflammation in AtherosclerosisAcute Kidney InjuryIschemia-Reperfusion SyndromeSingle Nucleotide Polymorphisms and InflammationPART VI: RESOLUTION OF INFLAMMATION AND TISSUE REPAIRPentraxins in the Orchestration of Defence and Tissue Repair During the Acute Phase ResponseAnti-inflammatory Cytokines, Soluble Receptors, and Natural AntagonistsRegulatory T CellsLeukocyte ReprogrammingRoles of Specialized Proresolving Lipid Mediators in Inflammation-Resolution and Tissue RepairGlucocorticoidsThe Neuroimmune Communicatome in InflammationThe Inflammatory Response in Tissue RepairPART VII: DETECTION AND TREATMENTSBiomarkers in InflammationIn Vivo Imaging of InflammationNovel Targets for Drug DevelopmentInflammation, Microbiota and Gut ReconditioningNatural Products as Source of Anti-Inflammatory Drugs