Molecular Imaging in the Clinical Neurosciences

While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function.  In Molecular Imaging in the Clinical Neurosciences, experts in the field provide the reader with up-to-date information on the basic principles of molecular imaging and its major applications in the clinical neurosciences. Beginning with a section offering a comprehensive review of the methodological foundations from physics, chemistry, and mathematics including mathematical modeling, essential for meaningful data analysis, this detailed volume then continues with sections on the major biological principles and neurochemical targets relevant in current neuroimaging research and the major clinical applications from the fields of psychiatry and neurology.  Written for the popular Neuromethods series, this work contains the kind of key description and implementation advice that guarantees successful results.Authoritative and cutting-edge, Molecular Imaging in the Clinical Neurosciences serves as a helpful source of knowledge for both basic and clinical scientists from psychology, psychiatry, neurology, nuclear medicine, nuclear chemistry, and the associated disciplines, all of which makes molecular imaging such a rewarding, interdisciplinary field of work.

Provides readers with up-to-date information on the basic principles of molecular imaging and its major applications in clinical neuroscience

1. Instrumentation and Physical Principles            Christoph Weirich and Hans Herzog 2. Molecular Neuroscience and the Quantification of Brain Dynamics            Albert Gjedde and Dean F. Wong 3. Radiopharmaceutical Chemistry            Markus Piel and Frank Rösch 4. Introduction to the Basics of Magnetic Resonance Imaging            Klaus Möllenhoff, Ana-Maria Oros-Peusquens, and N. Jon Shah 5. Quantification of Cerebral Blood Flow            Adriaan A. Lammertsma 6. The Assay of Enzyme Activity by Positron Emission Tomography            Paul Cumming and Neil Vasdev 7. Molecular Imaging Studies of Second Messenger Pathways: Looking Deeper than the Membrane            Paul Cumming and Neil Vasdev 8. Quantification of Neuroreceptors and Neurotransporters            Hiroshi Ito, Mika Naganawa, Chie Seki, Harumasa Takano, Iwao Kanno, and Tetsuya Suhara 9. Measuring Dopamine Synaptic Transmission with Molecular Imaging and Pharmacological Challenges: The State of the Art            Marc Laruelle 10. Small Animal Imaging with Positron Emission Tomography (PET)            Hideo Tsukada 11. Emission Imaging in Dementia            Julie C. Price, Brian J. Lopresti, and Victor L. Villemagne 12. Neurochemical Imaging of Addictive Disorders            Allegra Broft and Diana Martinez 13. Molecular Imaging of Mood Disorders            Jeffrey H. Meyer 14. Molecular Imaging in Schizophrenia            Oliver Howes 15. Imaging the Pathophysiology of Ischemic Cerebrovascular Disease            Wolf-Dieter Heiss 16. Molecular Imaging of Brain Tumors            Karl-Josef Langen 17. Molecular Imaging in Parkinson¿s Disease            Laura K. Teune and Karl L. Leenders 18. Epilepsy            Alexander Hammers            Christoph Weirich and Hans Herzog