ABC of Colorectal Cancer

Colorectal cancer is a common cause of morbidity and mortality inwhich prevention, screening and early detection are vital.Beginning with the patient perspective and following the patientpathway, this new second edition covers epidemiology andprevention, screening programmes, decision support networks, therole of primary care, and supportive care for patients withcolorectal cancer.The ABC of Colorectal Cancer provides the core knowledgeon clinical genetics, diagnosis, imaging, therapy and surgeryoptions and the latest evidence based guidelines for treating andmanaging colorectal cancer patients within the multidisciplinaryteam. Highly illustrated and accessible, it covers the fullspectrum of the disease to provide the basis to make a realdifference to clinical management.This is an invaluable practical guide for the non-specialist onall aspects of colorectal cancer, and is ideal for generalpractitioners, junior doctors, nurses and allied healthprofessionals.

Contributors viiPreface ix1 The Patient Perspective 1Kevin Bond2 Epidemiology and Prevention 4Peter Boyle, Patrick Mullie, Maria Paula Curado and David Zaridze3 Pathways of Carcinogenesis 8Michael Christie and Oliver Sieber4 Clinical Genetics in the Management of Colon Cancer 13Kai Ren Ong, Vicky Bowyer and Trevor Cole5 Screening for Colorectal Cancer 19Julietta Patnick and Wendy S. Atkin6 Decision Support Networks 22Matthew Kelly, Mark Austin and Sir Michael Brady7 Pathology of Colorectal Cancer 26Mohammad Ilyas8 Imaging of Colorectal Cancer 31Andrew Slater9 The Role of Primary Care 36Sue Wilson and Richard Hobbs10 Radiotherapy for Rectal Cancer 40Andrew Weaver11 Surgical Interventions 44Shazad Ashraf and Neil Mortensen12 Adjuvant Therapy 48Zenia Saridaki-Zoras and David Kerr13 Treatment of Advanced Disease 52David Watkins and David Cunningham14 Innovative Treatment for Colorectal Cancer 58Joanne L. Brady and David Kerr15 Supportive Care for Patients with Colorectal Cancer 63Pauline McCulloch and Annie Young16 Follow-up 69John PrimroseIndex 74