Basic Pharmacology

Written as an introductory pharmacology text, Basic Pharmacology: Understanding Drug Actions and Reactions provides the in-depth discussion of the chemical and molecular pharmacology fundamentals that pharmacy students require to move on to more advanced study. The book covers the principles of chemistry and biology necessary to understand drug action at the cellular level. It emphasizes the chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and interactions. The book effectively explains chemical and molecular pharmacology principles with extensive use of model drug structures. Written as an introductory pharmacology text, Basic Pharmacology: Understanding Drug Actions and Reactions provides the in-depth discussion of the chemical and molecular pharmacology fundamentals that pharmacy students require to move on to more advanced study. Employing the extensive use of model drug structures, the authors effectively explain chemical and molecular pharmacology principles. The book covers the principles of chemistry and biology necessary to understand drug action at the cellular level. It emphasizes the chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, and drug metabolism and interactions.

Structurally Non-Specific Drugs. Structurally Specific Drugs. Chemical Approaches to the Treatment of Cancer. Tutorial Examples. Problems. Drug Administration. Drug Absorption. Drug Distribution. Drug Elimination. Phase I Metabolic Reactions. Phase II Metabolic Reactions. Prodrugs. Drug Interactions. Clinical Correlation. Tutorial Example. Problems. References. Drug Receptors and Pharmacodynamics. Drug Induced Inhibition. Modes of Receptor Activation. Dose-Response Curves. Receptor Regulation. Receptor Signaling and Second Messenger Systems. Clinical Correlation.