Tietz Fundamentals of Clinical Chemistry and Molecular Diagn

Master clinical lab testing skills with the condensed version of the Tietz Textbook! Designed for use by CLS students, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 9th Edition provides a streamlined guide to the clinical chemistry knowledge you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry educator Nader Rifai, this textbook shows how to select and perform diagnostic lab tests, and how to accurately evaluate results. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Authoritative, foundational content mirrors that in the Tietz "bible" of laboratory medicine but in a more concise way. Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. Clinical cases from the Coakley Collection demonstrate how concepts from the text are applied in real-life scenarios. More than 400 illustrations and easy-to-read summary tables help you better understand and remember key concepts. Learning objectives, key words with definitions, and review questions are included in each chapter to make learning easier. NEW! Updated content throughout the text keeps you up to date on the latest techniques, instrumentation, and technologies. NEW! Additional questions are added to each chapter for subject reinforcement. NEW! Access to Adaptive Learning courses in clinical chemistry and molecular diagnostics is provided on the Evolve website.

PRINCIPLES OF LABORATORY MEDICINE1. Clinical Chemistry and Molecular Diagnostics 2. Analytical and Clinical Evaluation of Methods3. Preanalytical Variation4. Biological Variation and Analytical Performance Specifications5. Establishment and Use of Reference Intervals6. Specimen Collection, Processing, and Other Preanalytical Variables7. Quality Control of the Analytical Examination ProcessANALYTICAL TECHNIQUES AND INSTRUMENTATION8. Principles of Basic Techniques and Laboratory Safety 9. Optical Techniques 10. Electrochemistry and Chemical Sensors11. Electrophoresis  12. Chromatography 13. Mass Spectrometry  14. Enzyme and Rate Analyses15. Immunochemical Techniques  16. Automation in the Clinical Laboratory17. Point-of-Care TestingANALYTES18. Amino Acids, Peptides, and Proteins 19. Serum Enzymes20. Tumor Markers 21. Kidney Function Tests22. Carbohydrates 23. Lipids and Lipoproteins24. Electrolytes and Blood Gases 25. Hormones26. Catecholamines and Serotonin27. Vitamins and Trace Elements28. Hemoglobin and Iron29. Porphyrins and Porphyrias 30. Therapeutic Drug Monitoring31. Clinical Toxicology  32. Toxic elementsPATHOPHYSIOLOGY33. Diabetes Mellitus34. Cardiac Function35. Kidney Disease36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism37. Liver Disease38. Gastric, Intestinal and Pancreatic Function39. Bone and Mineral Metabolism40. Disorders of the Pituitary Gland41. Adrenal Cortex42. Thyroid Disorders43. Reproductive Endocrinology and Related Disorders44. Pregnancy and Prenatal Testing45. Newborn Screening and Inborn Errors of Metabolism46. PharmacogeneticsMOLECULAR DIAGNOSTICS47. Principles of Molecular Biology48. Genomes, Variants, and Massively Paralleled Methods49. Molecular MicrobiologyREFERENCE INFORMATION50. Appendix : Reference Information for the Clinical Laboratory