Polyphenols: Mechanisms of Action in Human Health and Disease

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products.

1. Polyphenols in the Prevention of Acute Pancreatitis in Preclinical Systems of Study: A Revisit2. Polyphenols as Supplements in Foods and Beverages: Recent Discoveries and Health Benefits, an Update3. Xanthohumol and the Medicinal Benefits of Beer4. Polyphenolic Flavonoids and Metalloprotease Inhibition: Applications to Health and Disease5. Biological and Pharmacological Effects of Polyphenolic Compounds From Ecklonia cava6. Clerodendrum volubile: Phenolics and Applications to Health7. Eryngium campestre L.: Polyphenolic and Flavonoid Compounds; Applications to Health and Disease 8. Antioxidant Activity of Anthocyanins in Common Legume Grains9. Tomato Polyphenolics: Putative Applications to Health and Disease10. Polyphenolic Compounds in Sweet Cherries: A Focus on Anthocyanins 11. Citrus Fruit Polyphenols and Flavonoids: Applications to Psychiatric Disorders12. Anthocyanins and Diabetes Regulation13. The Role of Direct and Indirect Polyphenolic Antioxidants in Protection Against Oxidative Stress14. Role of Protocatechuic Acid in Obesity-Related Pathologies: An Update15. Exposure to Polyphenolic Compounds Modulates Type 1 Diabetes: The Case of Genistein16. Chocolate/Cocoa Polyphenols and Oxidative Stress17. An Overview of Dietary Polyphenols and Their Therapeutic Effects18. The Polyphenolic Compound Resveratrol Attenuates Pain: Neurophysiological Mechanisms19. Possible Benefits and Risks of Polyphenols Supplementation During Pregnancy20. Flavonoids as Modulators of Neutrophils' Oxidative Burst: Structure-Activity Relationship21. Manipulation of Mitochondrial Function by Polyphenols for New Treatment Strategies22. Bioavailability of Flavonoids: The Role of Cell Membrane Transporters23. Interaction of Polyphenols with the Intestinal and Placental Absorption of Some Bioactive Compounds 24. Analyzing Ingredients in Dietary Supplements and Their Metabolites25. Metabolism of Dietary Polyphenols by Human Gut Microbiota and Their Health Benefits26. Bioavailability and Biochemistry of Quercetin and Applications to Health and Diseases27. Effects of Quercetin and Its Combinations on Health28. Green Tea Polyphenols in the Amelioration of Osteoarthritis: Memoir on the Preclinical Observations 29. Polyphenolics Evoke Healing Responses: Clinical Evidence and Role of Predictive Biomarkers 40330. Hepatoprotective Effects of Green Tea and Its Polyphenols: A Revisit31. CAPE and Tympanosclerosis 32. The Polyphenolic Compound Hesperidin and Bone Protection